Movies like Protocolo 48: El experimento final (2012)
The best movies like Protocolo 48: El experimento final (2012) are Return to... Return to Nuke 'Em High aka Vol. 2 (2017), Infestation (2009) and Asylum: Twisted Horror and Fantasy Tales (2020). If Protocolo 48: El experimento final hooked you with its comedy and science fiction, these 20 similar films are what to watch next, and every pick says why it matches.

Quick picks
- Highest ratedLa Leyenda de los Chaneques (2023)8.4/10 from 287 votes
- NewestAfterburn (2025)Released 2025
- In SpanishLa Leyenda de los Chaneques (2023)Also in Spanish
Return to... Return to Nuke 'Em High aka Vol. 2 (2017)
Following the events of Volume 1, the mutated glee club continue their violent rampage in Tromaville. Chrissy and Lauren, two innocent lesbian lovers, must fight not only the Cretins, mutants, and monsters but also the evil Tromorganic Foodstuffs Conglomerate. Can they, and Kevin the Wonder Duck, save Tromaville High School and the world?
Why it matches: Recommended by TMDB viewers · both comedy & horror
Popcorn FlickMovies like thisInfestation (2009)
After being stung by a giant insect, Cooper learns that these bugs are attacking the whole city. He joins forces with the survivors, in order to find a way to counter-attack.
Why it matches: Recommended by TMDB viewers · both comedy & horror
SnoozefestMovies like thisAsylum: Twisted Horror and Fantasy Tales (2020)
Brandon prepares to give his last stand-up comedy show. As his stories and jokes pass, the public begins to cheer up. But at that precise moment Brandon will realize that these stories have a strong relationship with his past. More than he imagines.
Why it matches: Recommended by TMDB viewers · both comedy & horror
SnoozefestMovies like thisSnatchers (2019)
After status-obsessed teen Sara has sex for the first time, she wakes up the next day nine months pregnant-with an alien.
Why it matches: Recommended by TMDB viewers · both science fiction & horror
Popcorn FlickMovies like thisIck (2025)
Science teacher Hank’s life changes when he reconnects with his first love and suspects that a new student may be his daughter—all while facing an alien threat in their town.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisFreaks of Nature (2015)
In the town of Dillford, humans, vampires and zombies were all living in peace - until the alien apocalypse arrived. Now three teenagers-one human, one vampire, and one zombie-have to team up to figure out how to get rid of the visitors.
Why it matches: Recommended by TMDB viewers · both science fiction & comedy
Popcorn FlickMovies like thisFreaked (1993)
A vain actor, his best friend, and an activist end up at a mutant freak farm run by a weirdo scientist.
Why it matches: Recommended by TMDB viewers · both comedy & science fiction
Popcorn FlickMovies like thisTremors: Shrieker Island (2020)
When a group of hunters genetically modify Graboid eggs, they face an all-out war against the larger, terrifyingly intelligent creatures, and swiftly multiplying Shriekers!
Why it matches: Recommended by TMDB viewers · both comedy & horror
Popcorn FlickMovies like thisThe Lost Skeleton of Cadavra (2001)
A dedicated scientist, aided by his clueless wife, rolls up his shirt sleeves and tries to save the world from a radioactive monster, curious space aliens, an evil scientist and a crabby skeleton.
Why it matches: Recommended by TMDB viewers · both comedy & horror
Popcorn FlickMovies like thisRelax, I'm from the Future (2023)
Casper is a time traveller who arrives in the 2020s in an attempt to prevent a major future catastrophe. He meets Holly, a queer black woman he befriends and draws into his plan by giving her his knowledge of the future so that she can make quick money. However, they unwittingly alter the future themselves with their actions, until Doris, another time traveller, arrives to stop them.
Why it matches: Recommended by TMDB viewers · both comedy & science fiction
SnoozefestMovies like thisLa Leyenda de los Chaneques (2023)
Five years after giving up his powers and separating from his friends, Leo San Juan has started a new life trying to focus on his family and their bakery, staying away from danger and adventures. However, Leo knows that his plans are rarely fulfilled and this time is no exception: while traveling with Nando to Veracruz, things start to get weird, and from the depths of the Tuxtlas jungle, an ancient curse has returned and only Leo can face it.
Why it matches: Recommended by TMDB viewers · both comedy & horror
Absolute CinemaMovies like thisAfterburn (2025)
Set against the backdrop of a postapocalyptic Earth whose Eastern Hemisphere was destroyed by a massive solar flare, leaving what life remains mutated from radiation and fallout. The story revolves around a group of treasure hunters who extract such objects as the Mona Lisa, the Rosetta Stone and the Crown Jewels while facing rival hunters, mutants and pirates.
Why it matches: Recommended by TMDB viewers · both science fiction & comedy
Popcorn FlickMovies like thisPower Rangers Samurai: Clash of the Red Rangers - The Movie (2011)
The Samurai Rangers team up with the mysterious RPM Ranger Red to fight off Master Xandred's Mooger army and a robotic supervillain from the RPM Ranger's dimension. But when both Red Rangers get struck with hypnobolts, they turn against one another.
Why it matches: Recommended by TMDB viewers · both comedy & science fiction
Worth the HypeMovies like thisExtinction (2015)
And suddenly, overnight, the world came to a halt. Two men, two survivors, one kid, and hatred that separates them. A place forgotten by everyone, including the creatures that inhabit the Earth... until now.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisMonster Hunters (2020)
When an alien prison ship crash lands and unleashes creature after creature in the California desert, they make quick work of the army that tries to stop them. Now, the only hope of stopping the aliens rests with a secret branch of the government specializing in alien weaponry. But with the team untested in actual combat, the battle for Earth will be brutal.
Why it matches: Recommended by TMDB viewers · both science fiction & horror
Popcorn FlickMovies like thisResident Evil (2002)
When a virus leaks from a top-secret facility, turning all resident researchers into ravenous zombies and their lab animals into mutated hounds from hell, the government sends in an elite military task force to contain the outbreak.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisReal Men (1987)
A womanizing CIA agent and an insecure insurance agent are paired together to make sure a deal goes through with aliens for the future of mankind.
Why it matches: Recommended by TMDB viewers · both comedy & science fiction
Popcorn FlickMovies like thisZygote (2017)
The two remaining crew members of a mining operation in the Arctic Circle fight to survive against an alien creature.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Worth the HypeMovies like thisThe Bed Sitting Room (1969)
In the hazy aftermath of World War III, the fallout from a 'nuclear misunderstanding' is producing strange mutations amongst the survivors, and the noble Lord Fortnum finds himself transforming into a bed sitting room.
Why it matches: Recommended by TMDB viewers · both comedy & science fiction
SnoozefestMovies like thisSleeper (1973)
Miles Monroe, a clarinet-playing health food store proprietor, is revived out of cryostasis 200 years into a future world in order to help rebels fight an oppressive government regime.
Why it matches: Recommended by TMDB viewers · both comedy & science fiction
Popcorn FlickMovies like this
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Frequently asked questions
What are the best movies like Protocolo 48: El experimento final?
The closest matches to Protocolo 48: El experimento final are Return to... Return to Nuke 'Em High aka Vol. 2 (2017), Infestation (2009) and Asylum: Twisted Horror and Fantasy Tales (2020). Below are 17 more, each with the reason it matches.
What should I watch after Protocolo 48: El experimento final?
Start with Return to... Return to Nuke 'Em High aka Vol. 2 (2017), the closest match to Protocolo 48: El experimento final.
What is the highest-rated movie like Protocolo 48: El experimento final?
La Leyenda de los Chaneques (2023), rated 8.4/10 by 287 TMDB users.
What is the newest movie like Protocolo 48: El experimento final?
Afterburn (2025) is the most recent release on this list.
Are there Spanish movies like Protocolo 48: El experimento final?
Yes: La Leyenda de los Chaneques (2023).
How are movies similar to Protocolo 48: El experimento final chosen?
First come films that Trakt’s viewers watch alongside Protocolo 48: El experimento final, then TMDB’s recommendations and films it rates as similar in story and genre. Each pick says which signal put it there.



















