Movies like Patient Zero (2014)
The best movies like Patient Zero (2014) are Abduction (2019), Containment (2015) and Zygote (2017). If Patient Zero hooked you with its science fiction and horror, these 20 similar films are what to watch next, and every pick says why it matches.
Quick picks
- Highest ratedThe Return (2020)6.7/10 from 327 votes
- NewestOsiris (2025)Released 2025
Abduction (2019)
A man steps out of a park fountain in Ho Chi Minh City with no recollection of who he is or where he came from. As he wanders through the city, piecing together clues to his past, he is relentlessly pursued by mysterious figures.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisContainment (2015)
Neighbors in a block wake one morning to find they have been sealed inside their apartments. Can they work together to find out why? Or will they destroy each other in their fight to escape?
Why it matches: Recommended by TMDB viewers · both horror & science fiction
SnoozefestMovies like thisZygote (2017)
The two remaining crew members of a mining operation in the Arctic Circle fight to survive against an alien creature.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Worth the HypeMovies like thisAlien: Alone (2019)
An abandoned crew member aboard a derelict chemical hauler is trying to keep her ship and herself alive. After discovering hidden cargo, she risks it all to power up the broken ship in search of human life.
Why it matches: Recommended by TMDB viewers · both science fiction & horror
Popcorn FlickMovies like thisBlood and Snow (2023)
When researchers rescue a fellow scientist who survived a meteorite strike in the Arctic, they discover she may not be who they think she is. Is she some-how changed?
Why it matches: Recommended by TMDB viewers · both science fiction & horror
Popcorn FlickMovies like thisDark Light (2019)
A woman returns to her family home and discovers it to be inhabited by monsters.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisBooks of Blood (2020)
A journey into uncharted and forbidden territory through three tales tangled in space and time.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisThe Signal (2007)
A horror film told in three parts, from three perspectives, in which a mysterious transmission that turns people into killers invades every cell phone, radio, and television.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
SnoozefestMovies like thisDie Alone (2024)
Lost in a world reclaimed by nature and overrun by mysterious creatures, Ethan, a young man with amnesia navigates the dangerous landscape in search of his lost love Emma. His journey takes an unexpected turn when he encounters Mae, a hardened and eccentric survivor. Together, Ethan and Mae face threats both human and otherwise before a fateful encounter with Kai unravels a secret that lies just beyond Ethan's fractured memory.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisSlash/Back (2022)
In a remote Arctic community, a group of Inuit girls fight off an alien invasion, all while trying to make it to the coolest party in town.
Why it matches: Recommended by TMDB viewers · both science fiction & horror
Popcorn FlickMovies like thisThe Resurrected (1991)
Charles Dexter Ward, a wealthy scientist, uses an ancient diary and human remains to begin a terrifying and bloody pursuit for immortality.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisDaylight's End (2016)
Years after a mysterious plague has devastated the planet and turned most of humanity into blood-hungry creatures, a rogue drifter on a vengeful hunt stumbles across a band of survivors in an abandoned police station and reluctantly agrees to try to help them defend themselves and escape to the sanctuary they so desperately need.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
SnoozefestMovies like thisYear 10 (2024)
After the fall of civilization, the few survivors have been driven to cannibalism. A young man must confront a violent tribe that has murdered his father and stolen the medicine that keeps his girlfriend alive.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisMonster Hunters (2020)
When an alien prison ship crash lands and unleashes creature after creature in the California desert, they make quick work of the army that tries to stop them. Now, the only hope of stopping the aliens rests with a secret branch of the government specializing in alien weaponry. But with the team untested in actual combat, the battle for Earth will be brutal.
Why it matches: Recommended by TMDB viewers · both science fiction & horror
Popcorn FlickMovies like thisExtinction (2015)
And suddenly, overnight, the world came to a halt. Two men, two survivors, one kid, and hatred that separates them. A place forgotten by everyone, including the creatures that inhabit the Earth... until now.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisThe Return (2020)
After the death of his father, a brilliant college student returns to his family home where he learns that the horrors from his childhood aren't as dead and gone as he once thought.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisOsiris (2025)
Special Forces commandos on a mission are abducted mid-operation by a mysterious spacecraft. Upon waking aboard, they find themselves prey to a relentless alien race in a fight for survival.
Why it matches: Recommended by TMDB viewers · both science fiction & horror
Popcorn FlickMovies like thisDouble Blind (2024)
After an experimental drug trial goes awry, the test subjects face a terrifying side effect: if you fall asleep you die. Trapped in an isolated facility, panic ensues as they try to escape and somehow stay awake.
Why it matches: Recommended by TMDB viewers · both horror & science fiction
Popcorn FlickMovies like thisGod Is a Bullet (2023)
Vice detective Bob Hightower finds his ex-wife murdered and daughter kidnapped by a cult. Frustrated by the botched official investigations, he quits the force and infiltrates the cult to hunt down the leader with the help of the cult’s only female victim escapee, Case Hardin.
Why it matches: Recommended by TMDB viewers · both horror
Popcorn FlickMovies like thisEradication (2022)
When an unknown disease wipes out most of the world’s population, a man with unique blood is isolated for study. Fearing for his wife’s safety, he breaks his quarantine – into a world overrun by monstrous Infected and a shadowy agency hunting them down.
Why it matches: Recommended by TMDB viewers · both horror
Popcorn FlickMovies like this
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Frequently asked questions
What are the best movies like Patient Zero?
The closest matches to Patient Zero are Abduction (2019), Containment (2015) and Zygote (2017). Below are 17 more, each with the reason it matches.
What should I watch after Patient Zero?
Start with Abduction (2019), the closest match to Patient Zero.
What is the highest-rated movie like Patient Zero?
The Return (2020), rated 6.7/10 by 327 TMDB users.
What is the newest movie like Patient Zero?
Osiris (2025) is the most recent release on this list.
Are there English movies like Patient Zero?
Yes: Abduction (2019), Containment (2015) and Zygote (2017).
How are movies similar to Patient Zero chosen?
First come films that Trakt’s viewers watch alongside Patient Zero, then TMDB’s recommendations and films it rates as similar in story and genre. Each pick says which signal put it there.