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Movies like Man with the Screaming Brain (2005)

The best movies like Man with the Screaming Brain (2005) are Infestation (2009), Asylum: Twisted Horror and Fantasy Tales (2020) and Re-Animator (1985). If Man with the Screaming Brain hooked you with its comedy and horror, these 30 similar films are what to watch next, and every pick says why it matches.

Quick picks

  1. Infestation (2009)

    After being stung by a giant insect, Cooper learns that these bugs are attacking the whole city. He joins forces with the survivors, in order to find a way to counter-attack.

    Why it matches: Recommended by TMDB viewers · both comedy & horror

  2. Asylum: Twisted Horror and Fantasy Tales (2020)

    Brandon prepares to give his last stand-up comedy show. As his stories and jokes pass, the public begins to cheer up. But at that precise moment Brandon will realize that these stories have a strong relationship with his past. More than he imagines.

    Why it matches: Recommended by TMDB viewers · both comedy & horror

  3. Re-Animator (1985)

    Conducting clandestine experiments within the morgue at Miskatonic University, scientist Herbert West reveals to a fellow graduate student his groundbreaking work concerning the re-animation of fresh corpses.

    Why it matches: Recommended by TMDB viewers · both science fiction & comedy

    Worth the HypeMovies like this
  4. Adult Swim Yule Log (2022)

    Get in the holiday spirit with this cozy, crackling fire.

    Why it matches: Recommended by TMDB viewers · both comedy & horror

    Popcorn FlickMovies like this
  5. Cold Storage (2026)

    When a mutating, highly contagious fungus escapes a sealed facility, two employees – joined by a grizzled bioterror operative – must survive the wildest night shift ever to save humanity from extinction.

    Why it matches: Recommended by TMDB viewers · both horror & science fiction

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  6. Frankenhooker (1990)

    A medical school dropout loses his fiancée in a tragic lawnmower incident and decides to bring her back to life. Unfortunately, he was only able to save her head, so he goes to the red light district in the city and lures prostitutes into a hotel room so he can collect body parts to reassemble her.

    Why it matches: Recommended by TMDB viewers · both comedy & horror

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  7. Bad Taste (1987)

    A team from the intergalactic fast food chain Crumb's Crunchy Delights descends on Earth, planning to make human flesh the newest taste sensation. After they wipe out the New Zealand town Kaihoro, the country’s Astro-Investigation and Defense Service (AIaDS) is called in to deal with the problem. Things are complicated due to Giles, an aid worker who comes to Kaihoro the same day to collect change from the residents. He is captured by the aliens, and AIaDS stages a rescue mission that quickly becomes an all-out assault on the aliens’ headquarters.

    Why it matches: Recommended by TMDB viewers · both comedy & horror

    Popcorn FlickMovies like this
  8. Ick (2025)

    Science teacher Hank’s life changes when he reconnects with his first love and suspects that a new student may be his daughter—all while facing an alien threat in their town.

    Why it matches: Recommended by TMDB viewers · both horror & science fiction

    Popcorn FlickMovies like this
  9. Bride of Re-Animator (1990)

    Unperturbed by the disastrous outcome of his previous meddling with the dead, Dr. West continues his research into the phenomenon of re-animation; only this time, he plans to create life – starting with the heart of his young protégé Dan's dearly deceased Meg Halsey.

    Why it matches: Recommended by TMDB viewers · both horror & comedy

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  10. Clayface (2026)

    Matt Hagen's meteoric rise from Gotham street kid to Hollywood leading man is tragically cut short when a local crime boss's actions leave him horribly disfigured. Abandoned by his team and with nothing left, Matt seeks out a cutting edge treatment that miraculously returns him to his former self… but also unexpectedly affects his grip on reality, spiraling him down a destructive path of all-consuming revenge.

    Why it matches: Recommended by TMDB viewers · both horror & science fiction

    Worth the HypeMovies like this
  11. Relax, I'm from the Future (2023)

    Casper is a time traveller who arrives in the 2020s in an attempt to prevent a major future catastrophe. He meets Holly, a queer black woman he befriends and draws into his plan by giving her his knowledge of the future so that she can make quick money. However, they unwittingly alter the future themselves with their actions, until Doris, another time traveller, arrives to stop them.

    Why it matches: Recommended by TMDB viewers · both comedy & science fiction

  12. Osiris (2025)

    Special Forces commandos on a mission are abducted mid-operation by a mysterious spacecraft. Upon waking aboard, they find themselves prey to a relentless alien race in a fight for survival.

    Why it matches: Recommended by TMDB viewers · both science fiction & horror

    Popcorn FlickMovies like this
  13. The Girl with All the Gifts (2016)

    In the future, a strange fungus has changed nearly everyone into thoughtless, flesh-eating monsters. When a scientist and a teacher find a girl who seems to be immune to the fungus, they all begin a journey to save humanity.

    Why it matches: Recommended by TMDB viewers · both horror & science fiction

    Popcorn FlickMovies like this
  14. The Hidden (1987)

    When average, law-abiding citizens suddenly turn to a life of hedonistic behavior and violent crime, Detective Tom Beck is tasked with helping young FBI agent Lloyd Gallagher determine the cause.

    Why it matches: Recommended by TMDB viewers · both science fiction & horror

    Popcorn FlickMovies like this
  15. Britannia Hospital (1982)

    Britannia Hospital, an esteemed English institution, is marking its gala anniversary with a visit by the Queen Mother herself. But when investigative reporter Mick Travis arrives to cover the celebration, he finds the hospital under siege by striking workers, ruthless unions, violent demonstrators, racist aristocrats, an African cannibal dictator, and sinister human experiments.

    Why it matches: Recommended by TMDB viewers · both comedy & science fiction

    Popcorn FlickMovies like this
  16. Good Luck, Have Fun, Don't Die (2026)

    A 'Man from the Future' arrives at an LA diner where he must recruit the precise combination of disgruntled patrons to join him on a one-night quest to save the world from the terminal threat of a rogue artificial intelligence.

    Why it matches: Recommended by TMDB viewers · both science fiction & comedy

    Worth the HypeMovies like this
  17. Die Alone (2024)

    Lost in a world reclaimed by nature and overrun by mysterious creatures, Ethan, a young man with amnesia navigates the dangerous landscape in search of his lost love Emma. His journey takes an unexpected turn when he encounters Mae, a hardened and eccentric survivor. Together, Ethan and Mae face threats both human and otherwise before a fateful encounter with Kai unravels a secret that lies just beyond Ethan's fractured memory.

    Why it matches: Recommended by TMDB viewers · both horror & science fiction

    Popcorn FlickMovies like this
  18. Extinction (2015)

    And suddenly, overnight, the world came to a halt. Two men, two survivors, one kid, and hatred that separates them. A place forgotten by everyone, including the creatures that inhabit the Earth... until now.

    Why it matches: Recommended by TMDB viewers · both horror & science fiction

    Popcorn FlickMovies like this
  19. Vampire's Kiss (1989)

    A publishing executive is visited and bitten by a vampire and starts exhibiting erratic behavior. He pushes his secretary to extremes as he tries to come to terms with his affliction.

    Why it matches: Recommended by TMDB viewers · both comedy & horror

    Popcorn FlickMovies like this
  20. Bad (1977)

    Hazel runs a beauty salon out of her house, but makes extra money by providing ruthless women the oppurtunity to perform hit jobs. L.T. is a parasite, and contacts Hazel looking for work after he runs out of money. She is reluctant to use him for a hit, since she prefers using women, but decides to try him on a trial basis. Meanwhile, the cop she pays off wants an arrest to make it look like he's doing his job, but Hazel doesn't want to sacrifice any of her "associates". The sleazy side of life is explored in this delightfully dark and deadpan film.

    Why it matches: Recommended by TMDB viewers · both horror & comedy

    Popcorn FlickMovies like this
  21. Staycation (2023)

    As a candid interview carries on between the country's leading virologist and a no-nonsense journalist, a couple separated between continents play catch up while a pandemic rages across the globe.

    Why it matches: Similar story and style · both comedy & horror

  22. Dr. Jekyll and Mr. Hyde (1941)

    Dr. Jekyll believes good and evil exist in everyone and creates a potion that allows his evil side, Mr. Hyde, to come to the fore. He faces horrible consequences when he lets his dark side run amok.

    Why it matches: Similar story and style · both horror & science fiction

    Popcorn FlickMovies like this
  23. Frankenstein: The True Story (1974)

    Victor Frankenstein witnesses his creation turn uncontrollable after he's duped by his associate, Dr. Polidori.

    Why it matches: Similar story and style · both horror & science fiction

  24. Blackenstein (1973)

    Eddie is a Vietnam veteran who loses his arms and legs when he steps on a land mine, but a brilliant surgeon is able to attach new limbs. Unfortunately, an insanely jealous assistant (who has fallen in love with Eddie's fiancée) switches Eddie's DNA injections, transforming him into a gigantic killer.

    Why it matches: Similar story and style · both science fiction & horror

  25. Frankenstein Island (1981)

    Four balloonists and their dog are stranded on a remote island with a woman believed to be a descendant of Frankenstein, who is conducting experiments on lost sailors.

    Why it matches: Similar story and style · both horror & science fiction

  26. Frankenstein Meets the Space Monster (1965)

    When an atomic war on Mars destroys the planet's women, it's up to Martian Princess Marcuzan and her right-hand man Dr. Nadir to travel to earth and kidnap women for new breeding stock. Landing in Puerto Rico, they shoot down a NASA space capsule manned by an android. With his electronic brain damaged, the android terrorizes the island while the Martians raid beaches and pool parties

    Why it matches: Similar story and style · both horror & science fiction

  27. American Splendor (2003)

    An original mix of fiction and reality illuminates the life of comic book hero everyman Harvey Pekar.

    Why it matches: Similar story and style · both comedy

    Worth the HypeMovies like this
  28. State of Bacon (2014)

    State of Bacon tells the kinda real but mostly fake tale of an oddball group of characters leading up to the annual Blue Ribbon Bacon Festival. Bacon-enthusiasts, Governor Branstad, a bacon queen, Hacksaw Jim Duggan, members of PETA, and an envoy of Icelanders are not excluded from this bacon party and during the course of the film become intertwined with the organizers of the festival to show that bacon diplomacy is not dead.

    Why it matches: Similar story and style · both comedy

  29. Calling Dr. Gillespie (1942)

    Dr. Kildare's friend Dr. Gillespie is called in to investigate when a young man suffering from mental problems disappears on a killing spree.

    Why it matches: Similar story and style · both comedy

  30. Death Line (1972)

    When a government official disappears in the London tunnels, after several reports of missing people in the same location, Scotland Yard start to take the matter seriously, along with a couple who stumble into a victim by accident.

    Why it matches: Similar story and style · both horror

Like Man with the Screaming Brain and something else?

Blend two favourites and we’ll find the films in between.

Frequently asked questions

What are the best movies like Man with the Screaming Brain?

The closest matches to Man with the Screaming Brain are Infestation (2009), Asylum: Twisted Horror and Fantasy Tales (2020) and Re-Animator (1985). Below are 27 more, each with the reason it matches.

What should I watch after Man with the Screaming Brain?

Start with Infestation (2009), the closest match to Man with the Screaming Brain.

What is the highest-rated movie like Man with the Screaming Brain?

Clayface (2026), rated 7.4/10 by 429 TMDB users.

What is the newest movie like Man with the Screaming Brain?

Clayface (2026) is the most recent release on this list.

Are there English movies like Man with the Screaming Brain?

Yes: Infestation (2009), Asylum: Twisted Horror and Fantasy Tales (2020) and Re-Animator (1985).

How are movies similar to Man with the Screaming Brain chosen?

First come films that Trakt’s viewers watch alongside Man with the Screaming Brain, then TMDB’s recommendations and films it rates as similar in story and genre. Each pick says which signal put it there.

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