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Movies like The Mutation (2021)

The best movies like The Mutation (2021) are Of Unknown Origin (1983), Willard (1971) and Nightmares (1983). If The Mutation hooked you with its horror, these 30 similar films are what to watch next, and every pick says why it matches.

Quick picks

  1. Of Unknown Origin (1983)

    A man who recently completed rebuilding a townhouse becomes obsessed with a rat infestation until it becomes an interspecies duel.

    Why it matches: Recommended by TMDB viewers · both horror

  2. Willard (1971)

    A social misfit, Willard is made fun of by his co-workers, and squeezed out of the company started by his deceased father by his boss. His only friends are a couple of rats he raised at home, Ben and Socrates. However, when one of them is killed at work, he goes on a rampage using his rats to attack those who have been tormenting him.

    Why it matches: Recommended by TMDB viewers · both horror

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  3. Nightmares (1983)

    A collection of short stories. In one a woman who leaves her house late at night to drive to the store while a killer is loose encounters some problems. In the second an arcade whiz kid's obsession with a game leads to deadly consequences. In the third a small town priest loses his faith and decides to leave town, but in the desert is stalked by a mysterious black pick-up truck. In the final story, a family's problem with a rat is larger than they think.

    Why it matches: Recommended by TMDB viewers · both horror

  4. Man-Made Monster (1941)

    Mad scientist turns a man into an electrically-controlled monster to do his bidding.

    Why it matches: Recommended by TMDB viewers · both horror

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  5. Deep Blue Sea (1999)

    Researchers on the undersea lab Aquatica have genetically altered the brains of captive sharks to develop a cure for Alzheimer's disease. But there's an unexpected side effect: the sharks got smarter, faster, and more dangerous. After a big storm damages their remote research facility, they must fight for their lives.

    Why it matches: Recommended by TMDB viewers · both horror

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  6. Splice (2010)

    Elsa and Clive, two rebellious young scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators — only to have that bond turn deadly.

    Why it matches: Recommended by TMDB viewers · both horror

  7. Alligator (1980)

    A baby alligator is flushed down a toilet and survives by eating discarded lab animals that have been injected with growth hormones. The now gigantic animal escapes the city sewers and goes on a rampage, pursued by a cop and a big-game hunter.

    Why it matches: Recommended by TMDB viewers · both horror

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  8. Mimic (1997)

    A disease carried by common cockroaches is killing Manhattan children. In an effort to stop the epidemic an entomologist, Susan Tyler, creates a mutant breed of insect that secretes a fluid to kill the roaches. This mutant breed was engineered to die after one generation, but three years later Susan finds out that the species has survived and evolved into a large, gruesome monster that can mimic human form.

    Why it matches: Recommended by TMDB viewers · both horror

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  9. Extinction (2015)

    And suddenly, overnight, the world came to a halt. Two men, two survivors, one kid, and hatred that separates them. A place forgotten by everyone, including the creatures that inhabit the Earth... until now.

    Why it matches: Recommended by TMDB viewers · both horror

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  10. The Fly (1986)

    When brilliant, eccentric scientist Seth Brundle makes a huge technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and the two become one.

    Why it matches: Recommended by TMDB viewers · both horror

    Worth the HypeMovies like this
  11. Clayface (2026)

    Matt Hagen's meteoric rise from Gotham street kid to Hollywood leading man is tragically cut short when a local crime boss's actions leave him horribly disfigured. Abandoned by his team and with nothing left, Matt seeks out a cutting edge treatment that miraculously returns him to his former self… but also unexpectedly affects his grip on reality, spiraling him down a destructive path of all-consuming revenge.

    Why it matches: Recommended by TMDB viewers · both horror

    Worth the HypeMovies like this
  12. The Brood (1979)

    A man tries to uncover an unconventional psychologist's therapy techniques on his institutionalised wife, amidst a series of brutal murders.

    Why it matches: Recommended by TMDB viewers · both horror

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  13. Resident Evil: Welcome to Raccoon City (2021)

    Once the booming home of pharmaceutical giant Umbrella Corporation, Raccoon City is now a dying Midwestern town. The company’s exodus left the city a wasteland…with great evil brewing below the surface. When that evil is unleashed, the townspeople are forever…changed…and a small group of survivors must work together to uncover the truth behind Umbrella and make it through the night.

    Why it matches: Recommended by TMDB viewers · both horror

  14. The Kindred (1987)

    Amanda's deathbed request to her son, John, was for him to destroy all the lab notes etc. from her last experiment. She also blurts out he had a brother. At the funeral John meets Melissa, who claims to be his mother's biggest fan. Together with some of John's friends they go to Amanda's house, but none are prepared for what they find there.

    Why it matches: Recommended by TMDB viewers · both horror

    Popcorn FlickMovies like this
  15. Beware Boiúna (2026)

    A medical mission deep in the Amazon becomes a desperate fight for survival when a colossal ancient predator awakens, turning the jungle into a deadly battleground where nature decides who lives and dies.

    Why it matches: Recommended by TMDB viewers · both horror

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  16. Werewolf of London (1935)

    A strange animal attack turns a botanist into a bloodthirsty monster.

    Why it matches: Recommended by TMDB viewers · both horror

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  17. American Mary (2013)

    A young medical student struggling to pay tuition is drawn into the shady world of underground body-modification.

    Why it matches: Recommended by TMDB viewers · both horror

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  18. Splinter (2008)

    When their plans for a nature trip go awry, Polly and boyfriend Seth decide to check into a motel. On their way, they're carjacked and kidnapped by low-rent crooks Dennis and Lacey, who take the victims and their SUV to a nearby gas station. Along the way, they encounter an increasingly terrifying horde of parasites, and if any of them intend to survive, they'll have to outsmart the deadly organisms.

    Why it matches: Recommended by TMDB viewers · both horror

    Popcorn FlickMovies like this
  19. Never Let Go (2024)

    As an evil takes over the world beyond their front doorstep, the only protection for a mother and her twin sons is their house and their family’s protective bond.

    Why it matches: Recommended by TMDB viewers · both horror

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  20. Resident Evil (2002)

    When a virus leaks from a top-secret facility, turning all resident researchers into ravenous zombies and their lab animals into mutated hounds from hell, the government sends in an elite military task force to contain the outbreak.

    Why it matches: Recommended by TMDB viewers · both horror

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  21. Dr. Drayce (2018)

    The 15 minute horror/thriller "Dr. Drayce" deals with the ill-fated relationship between the mad scientist Dr. Drayce and his greatest creation: his daughter, whom he created using the DNA of his deceased wife. When Dr. Drayce realizes that his daughter is misusing his scientific legacy to enrich herself through carrying out contract murders, he decides to destroy all that he possesses. He sends his last creation into a bloody struggle against the crew of elite killers: a struggle that has a deadly outcome for all involved.

    Why it matches: Similar story and style · both horror

  22. Cannibal Holocaust (1980)

    A New York University professor returns from a rescue mission to the Amazon rainforest with the footage shot by a lost team of documentarians who were making a film about the area's local cannibal tribes.

    Why it matches: Similar story and style · both horror

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  23. Dr. Renault's Secret (1942)

    A remake of the 1927 horror film "The Wizard". Dr. Larry Forbes arrives in a remote French village to visit his fiancée who lives with her scientist father Dr. Renault and his Ape-like manservant Noel. Several Murders coincide with Dr. Forbes arrival, with clues pointing in multiple directions.

    Why it matches: Similar story and style · both horror

  24. Bride of Re-Animator (1990)

    Unperturbed by the disastrous outcome of his previous meddling with the dead, Dr. West continues his research into the phenomenon of re-animation; only this time, he plans to create life – starting with the heart of his young protégé Dan's dearly deceased Meg Halsey.

    Why it matches: Similar story and style · both horror

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  25. Night of the Comet (1984)

    After a comet wipes out most of life on Earth, two Valley Girls find themselves fighting against cannibal zombies and a sinister group of scientists.

    Why it matches: Similar story and style · both horror

    Popcorn FlickMovies like this
  26. Bambi: The Reckoning (2025)

    After a mother and son get in a car wreck, they soon become hunted by Bambi, a mutated grief-stricken deer on a deadly rampage seeking revenge for the death of his mother and wife.

    Why it matches: Similar story and style · both horror

  27. Frogs (1972)

    Jason Crockett is an aging, grumpy, physically disabled millionaire who invites his family to his island estate for his birthday celebration. Pickett Smith is a free-lance photographer who is doing a pollution layout for an ecology magazine. Jason Crockett hates nature, poisoning anything that crawls on his property. On the night of his birthday the frogs and other members of nature begin to pay Crockett back.

    Why it matches: Similar story and style · both horror

  28. The Enjoyment of the Avacalho (2006)

    Sinners of a rural community having his flesh melted as an atonement for his Christian offenses. A revolutionary army of two people feuding with hordes of rotting zombies, and a mad scientist philosopher that builds a mummy of Christ to control the world.

    Why it matches: Similar story and style · both horror

  29. Piranha (1978)

    When flesh-eating piranhas are accidentally released into a summer resort's rivers, the guests become their next meal.

    Why it matches: Similar story and style · both horror

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  30. Cujo (TBA)

    Based on the Stephen King bestselling novel.

    Why it matches: Similar story and style · both horror

Like The Mutation and something else?

Blend two favourites and we’ll find the films in between.

Frequently asked questions

What are the best movies like The Mutation?

The closest matches to The Mutation are Of Unknown Origin (1983), Willard (1971) and Nightmares (1983). Below are 27 more, each with the reason it matches.

What should I watch after The Mutation?

Start with Of Unknown Origin (1983), the closest match to The Mutation.

What is the highest-rated movie like The Mutation?

The Fly (1986), rated 7.4/10 by 5,251 TMDB users.

What is the newest movie like The Mutation?

Clayface (2026) is the most recent release on this list.

Are there English movies like The Mutation?

Yes: Of Unknown Origin (1983), Willard (1971) and Nightmares (1983).

How are movies similar to The Mutation chosen?

First come films that Trakt’s viewers watch alongside The Mutation, then TMDB’s recommendations and films it rates as similar in story and genre. Each pick says which signal put it there.

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